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Article

Characterizing the role of atrial natriuretic peptide signaling in the development of embryonic ventricular conduction system.

Scientific reports - 2 May 2018

Govindapillai Arun, Hotchkiss Adam, Baguma-Nibasheka Mark, Rose Robert A, Miquerol Lucile, Smithies Oliver, Maeda Nobuyo, Pasumarthi Kishore B S

Abstract excerpt

Patients born with congenital heart defects frequently encounter arrhythmias due to defects in the ventricular conduction system (VCS) development. Although recent studies identified transcriptional networks essential for the heart development, there is scant information on the mechanisms regulating VCS development. Based on the association of atrial natriuretic peptide (ANP) expression with VCS forming regions,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels

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Source

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Identifiers

PMID: 29720615
DOI: 10.1038/s41598-018-25292-0
PMCID: PMC5932026

Genes

HCN4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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