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The role of Sphingolipids in myelination and myelin stability and their involvement in childhood and adult demyelinating disorders

28 Jul 2020

Abstract excerpt

Multiple sclerosis (MS) represents the most common demyelinating disease affecting the central nervous system (CNS) in adults as well as in children. Furthermore, in children, in addition to acquired diseases such as MS, genetically inherited diseases significantly contribute to the incidence of demyelinating disorders. Some genetic defects lead to sphingolipid alterations that are able to elicit neurological...

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PMID: 33448358
DOI: 10.1111/jnc.15133

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