Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children.

doi:10.1093/ibd/izy009

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Article

Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children.

Inflammatory bowel diseases - 18 May 2018

Spencer Elizabeth A, Davis Sonia M, Mack David R, Boyle Brendan M, Griffiths Anne M, LeLeiko Neal S, Sauer Cary G, Keljo David J, Markowitz James F, Baker Susan S, Rosh Joel R, Baldassano Robert N, Oliva-Hemker Maria, Pfefferkorn Marian D, Otley Anthony R, Heyman Melvin B, Noe Joshua D, Patel Ashish S, Rufo Paul A, Alison Marquis M, Walters Thomas D, Collins Margaret H, Kugathasan Subra, Denson Lee A, Hyams Jeffrey S, Dubinsky Marla C

Abstract excerpt

Background: In contrast to pediatric Crohn's disease (CD), little is known in pediatric ulcerative colitis (UC) about the relationship between disease phenotype and serologic reactivity to microbial and other antigens. Aim: The aim of this study was to examine disease phenotype and serology in a well-characterized inception cohort of children newly diagnosed with UC during the PROTECT Study (Predicting Response...

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PMID: 29718391
DOI: 10.1093/ibd/izy009
PMCID: PMC6093192

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