Age of diagnosis influences serologic responses in children with Crohn's disease: a possible clue to etiology?

doi:10.1002/ibd.20831

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Article

Age of diagnosis influences serologic responses in children with Crohn's disease: a possible clue to etiology?

Inflammatory bowel diseases - 1 May 2009

Markowitz James, Kugathasan Subra, Dubinsky Marla, Mei Ling, Crandall Wallace, LeLeiko Neal, Oliva-Hemker Maria, Rosh Joel, Evans Jonathan, Mack David, Otley Anthony, Pfefferkorn Marian, Bahar Ron, Vasiliauskas Eric, Wahbeh Ghassan, Silber Gary, Quiros J Antonio, Wrobel Iwona, Nebel Justin, Landers Carol, Picornell Yoanna, Targan Stephan, Lerer Trudy, Hyams Jeffrey

Abstract excerpt

BACKGROUND: Crohn's disease (CD) is often associated with antibodies to microbial antigens. Differences in immune response may offer clues to the pathogenesis of the disease. The aim was to examine the influence of age at diagnosis on the serologic response in children with CD. METHODS: Data were drawn from 3 North American multicenter pediatric inflammatory bowel disease (IBD) research consortia. At or shortly...

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PMID: 19107777
DOI: 10.1002/ibd.20831
PMCID: PMC2726983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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