Article
Plasmid-Mediated AmpC β-Lactamase and Underestimation of Extended-Spectrum β-Lactamase in Cefepime-Susceptible Elevated-Ceftazidime-MIC Enterobacteriaceae Isolates.
Japanese journal of infectious diseases - 24 Jul 2018
Nishimura Fumitaka, Morinaga Yoshitomo, Akamatsu Norihiko, Matsuda Junichi, Kaku Norihito, Takeda Kazuaki, Uno Naoki, Kosai Kosuke, Hasegawa Hiroo, Yanagihara Katsunori
Abstract excerpt
Phenotypic detection of extended-spectrum β-lactamase (ESBL) is important for public health and infection control; however, plasmid-mediated AmpC β-lactamases (pAmpCs) can interfere with the ESBL phenotyping. We focused on Enterobacteriaceae strains that were susceptible to cefepime but had a mildly elevated minimum inhibitory concentration (MIC) of ceftazidime and studied the effect of pAmpC on the ESBL...
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