Article
Improving the detection of patients with inherited predispositions to hematologic malignancies using next-generation sequencing-based leukemia prognostication panels.
Cancer - 1 Jul 2018
DiNardo Courtney D, Routbort Mark J, Bannon Sarah A, Benton Christopher B, Takahashi Koichi, Kornblau Steve M, Luthra Rajyalakshmi, Kanagal-Shamanna Rashmi, Medeiros L Jeffrey, Garcia-Manero Guillermo, M Kantarjian Hagop, Futreal P Andrew, Meric-Bernstam Funda, Patel Keyur P
Abstract excerpt
Recognizing and referring patients with possible inherited cancer predisposition syndromes for appropriate genetic evaluation and testing provides insights into optimal patient treatment approaches and also can provide education and testing opportunities for family members. Next-generation sequencing (NGS)-based, targeted genotyping for somatic mutations is increasingly used in the diagnosis, prognostication, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.