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Sarcopenic metabolomic profile reflected a sarcopenic phenotype associated with amino acid and essential fatty acid changes.

Metabolomics : Official journal of the Metabolomic Society - 8 Sept 2021

Opazo Rafael, Angel Bárbara, Márquez Carlos, Lera Lydia, Cardoso Dos Santos Gustavo R, Monnerat Gustavo, Albala Cecilia

Abstract excerpt

INTRODUCTION: Although sarcopenia greatly affects health and quality of life in older people, its pathophysiological causes are not fully elucidated. To face this challenge, omics technologies can be used. The metabolome gives a vision of the interaction between the genome and the environment through metabolic networks, thus contributing in clarifying the pathophysiology of the sarcopenic phenotype. OBJECTIVES:...

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PMID: 34498155
DOI: 10.1007/s11306-021-01832-0

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