Article
KDiamend: a package for detecting key drivers in a molecular ecological network of disease.
BMC systems biology - 11 Apr 2018
Lyu Mengxuan, Chen Jiaxing, Jiang Yiqi, Dong Wei, Fang Zhou, Li Shuaicheng
Abstract excerpt
BACKGROUND: Microbial abundance profiles are applied widely to understand diseases from the aspect of microbial communities. By investigating the abundance associations of species or genes, we can construct molecular ecological networks (MENs). The MENs are often constructed by calculating the Pearson correlation coefficient (PCC) between genes. In this work, we also applied multimodal mutual information (MMI) to...
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