Measuring phenotype-phenotype similarity through the interactome.

Abstract excerpt

BACKGROUND: Recently, measuring phenotype similarity began to play an important role in disease diagnosis. Researchers have begun to pay attention to develop phenotype similarity measurement. However, existing methods ignore the interactions between phenotype-associated proteins, which may lead to inaccurate phenotype similarity. RESULTS: We proposed a network-based method PhenoNet to calculate the similarity...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Databases, Genetic
• Share to Gene Expression Regulation