Article
A survey of functional genomic variation in domesticated chickens.
Genetics, selection, evolution : GSE - 16 Apr 2018
Derks Martijn F L, Megens Hendrik-Jan, Bosse Mirte, Visscher Jeroen, Peeters Katrijn, Bink Marco C A M, Vereijken Addie, Gross Christian, de Ridder Dick, Reinders Marcel J T, Groenen Martien A M
Abstract excerpt
BACKGROUND: Deleterious genetic variation can increase in frequency as a result of mutations, genetic drift, and genetic hitchhiking. Although individual effects are often small, the cumulative effect of deleterious genetic variation can impact population fitness substantially. In this study, we examined the genome of commercial purebred chicken lines for deleterious and functional variations, combining genotype...
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