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Article

Development of large-scale manufacturing of adipose-derived stromal cells for clinical applications using bioreactors and human platelet lysate.

Scandinavian journal of clinical and laboratory investigation - 1 Jul 2018

Haack-Sørensen Mandana, Juhl Morten, Follin Bjarke, Harary Søndergaard Rebekka, Kirchhoff Maria, Kastrup Jens, Ekblond Annette

Abstract excerpt

In vitro expanded adipose-derived stromal cells (ASCs) are a useful resource for tissue regeneration. Translation of small-scale autologous cell production into a large-scale, allogeneic production process for clinical applications necessitates well-chosen raw materials and cell culture platform. We compare the use of clinical-grade human platelet lysate (hPL) and fetal bovine serum (FBS) as growth supplements...

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Identifiers

PMID: 29661028
DOI: 10.1080/00365513.2018.1462082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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