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Article

Glu571 of PheT plays a pivotal role in the thermal stability of Escherichia coli PheRS enzyme.

Journal of basic microbiology - 1 Jun 2018

Ashwin Sri Bala Sridar, Madhumathi Irulappan, Vinodha Sengottuvel, Munavar M Hussain

Abstract excerpt

As of date the two temperature sensitive mutations isolated in pheST operon include pheS5 (G293 →A293 ) and pheT354. Recently, we reported that G673 of pheS defines a hot spot for intragenic suppressors of pheS5. In this investigation, in 13 independent experiments, a collection of temperature sensitive mutants were isolated by localized mutagenesis. Complementation using clones bearing pheS+ , pheT+ , and pheS+...

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Source

Identifiers

PMID: 29660847
DOI: 10.1002/jobm.201700645

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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