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Fully automated, on-site isolation of cfDNA from whole blood for cancer therapy monitoring.

Lab on a chip - 1 May 2018

Kim Chi-Ju, Park Juhee, Sunkara Vijaya, Kim Tae-Hyeong, Lee Yongjin, Lee Kyusang, Kim Mi-Hyun, Cho Yoon-Kyoung

Abstract excerpt

The potential utility of circulating tumour DNA (ctDNA) in patient blood for cancer diagnostics and real-time monitoring of disease progression is highly recognized. However, the lack of automated and efficient methods for cell-free DNA (cfDNA) isolation from peripheral blood has remained a challenge for broader acceptance of liquid biopsy in general clinical settings. Here, we demonstrate a lab-on-a-disc system...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29658031
DOI: 10.1039/c8lc00165k

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