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Cell-free DNA: the role in pathophysiology and as a biomarker in kidney diseases

1 Jan 2018

Abstract excerpt

Cell-free DNA (cfDNA) is present in various body fluids and originates mostly from blood cells. In specific conditions, circulating cfDNA might be derived from tumours, donor organs after transplantation or from the foetus during pregnancy. The analysis of cfDNA is mainly used for genetic analyses of the source tissue -tumour, foetus or for the early detection of graft rejection. It might serve also as a...

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PMID: 29343314
DOI: 10.1017/erm.2017.12

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