Article
Characterization and non-parametric modeling of the developing serum proteome during infancy and early childhood.
Scientific reports - 12 Apr 2018
Lietzén Niina, Cheng Lu, Moulder Robert, Siljander Heli, Laajala Essi, Härkönen Taina, Peet Aleksandr, Vehtari Aki, Tillmann Vallo, Knip Mikael, Lähdesmäki Harri, Lahesmaa Riitta
Abstract excerpt
Children develop rapidly during the first years of life, and understanding the sources and associated levels of variation in the serum proteome is important when using serum proteins as markers for childhood diseases. The aim of this study was to establish a reference model for the evolution of a healthy serum proteome during early childhood. Label-free quantitative proteomics analyses were performed for 103...
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