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The microRNA‐1908 up‐regulation in the peripheral blood cells impairs amyloid clearance by targeting ApoE

10 Apr 2018

Abstract excerpt

OBJECTIVE: To give a new insight into the mechanism of ApoE dysregulation and microRNA-1908 in Alzheimer's disease (AD). METHODS: Plasma ApoE levels were measured in 20 AD patients and 20 healthy controls. THP-1 was maintained in RPMI1640 with 10% fetal bovine serum. Quantitative real-time polymerase chain reaction was performed to detect 13-microRNA and ApoE mRNA in cultured cell lines. Enzyme-linked...

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PMID: 29635818
DOI: 10.1002/gps.4881

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