A genetic variant in IL-15Rα correlates with physical activity among European-American adults.

doi:10.1002/mgg3.368

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Article

A genetic variant in IL-15Rα correlates with physical activity among European-American adults.

Molecular genetics & genomic medicine - 1 May 2018

Bruneau Michael, Walsh Sean, Selinsky Eric, Ash Garrett, Angelopoulos Theodore J, Clarkson Priscilla, Gordon Paul, Moyna Niall, Visich Paul, Zoeller Robert, Thompson Paul, Gordish-Dressman Heather, Hoffman Eric, Devaney Joseph, Pescatello Linda S

Abstract excerpt

BACKGROUND: Interleukin-15 (IL-15) is a myokine associated with muscle strength, possibly by attenuating protein breakdown. A variant in the alpha-receptor (IL-15Rα 1775 A>C, rs2228059) partially modulates the muscle strength and size response to resistance training. We examined if this polymorphism associated with habitual physical activity among European-American adults. METHODS: Men (n = 240, 23.7 ± 0.3 year,...

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PMID: 29624921
DOI: 10.1002/mgg3.368
PMCID: PMC6014439

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