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Article

Novel GRN Mutations in Alzheimer's Disease and Frontotemporal Lobar Degeneration.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Piaceri Irene, Imperiale Daniele, Ghidoni Enrico, Atzori Cristiana, Bagnoli Silvia, Ferrari Camilla, Ungari Silvana, Ambrogio Luca, Sorbi Sandro, Nacmias Benedetta

Abstract excerpt

BACKGROUND: During the twentieth century, frontotemporal dementia (FTD) was often misdiagnosed, confused with Alzheimer's disease or psychiatric disorders, jeopardizing care and research. OBJECTIVE: To analyze the FTD genes in the DNA samples of patients belonging to families clinically classified as probable Alzheimer's disease (FAD) in the early 1990s and not carrying mutation in the three main genes linked to...

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Identifiers

PMID: 29614680
DOI: 10.3233/JAD-170989

Genes

GRN

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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