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Article

Novel Drosophila model for mitochondrial diseases by targeting of a solute carrier protein SLC25A46.

Brain research - 15 Jun 2018

Suda Kojiro, Ueoka Ibuki, Azuma Yumiko, Muraoka Yuuka, Yoshida Hideki, Yamaguchi Masamitsu

Abstract excerpt

Mutations in SLC25A46 gene have been identified in mitochondrial diseases that are sometimes classified as Charcot-Marie-Tooth disease type 2, optic atrophy and Leigh syndrome. Human SLC25A46 functions as a transporter across the outer mitochondrial membrane. However, it is still unknown how the neurodegeneration occurring in these diseases relates to the loss of SLC25A46 function. Drosophila has CG5755...

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Identifiers

PMID: 29604258
DOI: 10.1016/j.brainres.2018.03.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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