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Gastroenteropancreatic neuroendocrine neoplasms: genes, therapies and models

1 Feb 2018

Abstract excerpt

Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) refer to a group of heterogeneous cancers of neuroendocrine cell phenotype that mainly fall into one of two subtypes: gastroenteropancreatic neuroendocrine tumors (GEP-NETs; well differentiated) or gastroenteropancreatic neuroendocrine carcinomas (GEP-NECs; poorly differentiated). Although originally defined as orphan cancers, their steadily increasing...

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PMID: 29590641
DOI: 10.1242/dmm.029595

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