INTERRELATION OF THE GENE 4DKN1A (RS 1801270) POLYMORPHIC STATE AND LEVEL OF DEVELOPMENT OF CARIES IN CHILDREN WITH DOWN SYNDROME.

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INTERRELATION OF THE GENE 4DKN1A (RS 1801270) POLYMORPHIC STATE AND LEVEL OF DEVELOPMENT OF CARIES IN CHILDREN WITH DOWN SYNDROME.

Georgian medical news - 1 Feb 2018

Nazaryan R, Iskorostenskaya O, Gorenskaya O, Volkova N, Gargin V

Abstract excerpt

Study is devoted for rs1801270 polymorphism of CDKN1A gene due to the level of intensity of caries development in children with Down syndrome. The full development of oral cavity organs is ensured through a complex of genes whose protein products control different stages of this difficult process. Changes in gene structure, as well as disturbance of their expression may lead to abnormalities of development of...

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PMID: 29578436

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