Article
Small Subset of Adenoid Cystic Carcinoma of the Skin Is Associated With Alterations of the MYBL1 Gene Similar to Their Extracutaneous Counterparts.
The American Journal of dermatopathology - 1 Oct 2018
Kyrpychova Liubov, Vanecek Tomas, Grossmann Petr, Martinek Petr, Steiner Petr, Hadravsky Ladislav, Belousova Irena E, Shelekhova Ksenya V, Svajdler Marian, Dubinsky Pavol, Michal Michal, Kazakov Dmitry V
Abstract excerpt
Adenoid cystic carcinoma (ACC) of the skin is a rare malignant neoplasm histologically identical to homonymous tumors in other organs. Cutaneous ACC has been found to harbor MYB gene activations, either through MYB chromosomal abnormalities or by generation of the MYB-NFIB fusion. In salivary gland ACC, in addition to the MYB gene, alterations in MYBL1, the gene closely related to MYB, have been reported. We...
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