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Article

Diminished CD40L expression on T-cells in a case of disseminated cryptococcosis.

Indian journal of pathology & microbiology - 1 Jan 2000

Mohanty Supreet Kumar, Thakral Deepshi, Gupta Devika, Kumar Prabin, Mitra Dipendra Kumar

Abstract excerpt

X-linked hyperimmunoglobulin M (HIGM) syndrome may increase the susceptibility of patients to disseminated cryptococcal infections primarily due to CD40L deficiency that causes defective cross talk between T- and B-cells, thus preventing class switching. In HIGM syndrome, serum IgM levels are elevated with severe reduction in serum immunoglobulin G (IgG) and IgA levels. In addition, the expression of CD40L...

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Identifiers

PMID: 29567905
DOI: 10.4103/IJPM.IJPM_761_16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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