Article
QSurface: fast identification of surface expression markers in cancers.
BMC systems biology - 19 Mar 2018
Hong Yourae, Park Choa, Kim Nayoung, Cho Juyeon, Moon Sung Ung, Kim Jongmin, Jeong Euna, Yoon Sukjoon
Abstract excerpt
BACKGROUND: Cell surface proteins have provided useful targets and biomarkers for advanced cancer therapies. The recent clinical success of antibody-drug conjugates (ADCs) highlights the importance of finding selective surface antigens for given cancer subtypes. We thus attempted to develop stand-alone software for the analysis of the cell surface transcriptome of patient cancer samples and to prioritize lineage-...
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