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Article

Detection of RET (rearranged during transfection) variants and their downstream signal molecules in RET rearranged lung adenocarcinoma patients.

Surgical oncology - 1 Mar 2018

Kim Jeong-Oh, Shin Jung-Young, Kim Min Young, Son Kyoung Hwa, Jung Chan Kwon, Kim Tae-Jung, Kim Su Young, Park Jae Kil, Sung Sook Whan, Bae Sang Ju, Min Hyun Jung, Kang Jin-Hyoung

Abstract excerpt

BACKGROUND: We screened resected tumor tissues from patients with lung cancer for EGFR mutations, ALK rearrangements, and rearranged during transfection (RET) gene variants (including RET rearrangements and the Kinesin Family Member 5B (KIF5B)-RET fusion gene) using various methods including reverse transcription polymerase chain reaction (RT-PCR), transcript assays, fluorescence in situ hybridization (FISH), and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29549897
DOI: 10.1016/j.suronc.2018.01.006

Genes

RET
EGFR
ALK

Provenance

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