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<scp>RET</scp> expression and detection of <scp><i>KIF5B</i></scp>/<scp><i>RET</i></scp> gene rearrangements in Japanese lung cancer

12 Jul 2012

Abstract excerpt

RET encodes the tyrosine kinase receptor of growth factors belonging to the glial-derived neurotrophic factor family. Recently, RET gene rearrangements with N-terminal of KIF5B gene were identified in lung adenocarcinomas from large-scale sequencing. We investigated RET mRNA expression by real-time reverse-transcriptase polymerase chain reaction (RT-PCR) assay using LightCycler, and KIF5B/RET gene rearrangements...

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PMID: 23342255
DOI: 10.1002/cam4.13

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