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Article

Prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency among malaria patients in Upper Myanmar.

BMC infectious diseases - 16 Mar 2018

Lee Jinyoung, Kim Tae Im, Kang Jung-Mi, Jun Hojong, Lê Hương Giang, Thái Thị Lam, Sohn Woon-Mok, Myint Moe Kyaw, Lin Khin, Kim Tong-Soo, Na Byoung-Kuk

Abstract excerpt

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD; EC 1.1.1.49) deficiency is one of the most common X-linked recessive hereditary disorders in the world. Primaquine (PQ) has been used for radical cure of P. vivax to prevent relapse. Recently, it is also used to reduce P. falciparum gametocyte carriage to block transmission. However, PQ metabolites oxidize hemoglobin and generate excessive reactive oxygen...

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Identifiers

PMID: 29548282
DOI: 10.1186/s12879-018-3031-y
PMCID: PMC5857094

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