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Article

Characterization of G6PD genotypes and phenotypes on the northwestern Thailand-Myanmar border.

PloS one - 1 Jan 2014

Bancone Germana, Chu Cindy S, Somsakchaicharoen Raweewan, Chowwiwat Nongnud, Parker Daniel M, Charunwatthana Prakaykaew, White Nicholas J, Nosten François H

Abstract excerpt

Mutations in the glucose-6-phosphate dehydrogenase (G6PD) gene result in red blood cells with increased susceptibility to oxidative damage. Significant haemolysis can be caused by primaquine and other 8-aminoquinoline antimalarials used for the radical treatment of Plasmodium vivax malaria. The distribution and phenotypes of mutations causing G6PD deficiency in the male population of migrants and refugees in a...

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PMID: 25536053
DOI: 10.1371/journal.pone.0116063
PMCID: PMC4275285

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