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Matrix metalloproteinase-1 (MMP-1) and (MMP-8) gene polymorphisms promote increase and remodeling of the collagen III and V in posterior tibial tendinopathy.

Histology and histopathology - 1 Sept 2018

Diniz-Fernandes Tulio, Godoy-Santos Alexandre Leme, Santos Maria Cristina, Pontin Pedro, Pereira Caio Augusto Alves, Jardim Yuri Justi, Velosa Ana Paula Pereira, Maffulli Nicola, Teodoro Walcy Rosolia, Capelozzi Vera Luiza

Abstract excerpt

Posterior tibial tendinopathy (PTT) can lead to acquired flatfoot in adults. Many patients develop PTT without any identifiable risk factors. Molecular changes in extracellular matrix (ECM) and matrix metalloproteinase (MMP) polymorphism may influence the risk of developing PTT. We aim to investigate the association between matrix metalloproteinase-1 (MMP-1) and (MMP-8) gene polymorphisms with changes in collagen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29532899
DOI: 10.14670/HH-11-982

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