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A Mitochondrial Health Index Sensitive to Mood and Caregiving Stress

3 Feb 2018

Abstract excerpt

BACKGROUND: Chronic life stress, such as the stress of caregiving, can promote pathophysiology, but the underlying cellular mechanisms are not well understood. Chronic stress may induce recalibrations in mitochondria leading to changes either in mitochondrial content per cell, or in mitochondrial functional capacity (i.e., quality). METHODS: Here we present a functional index of mitochondrial health (MHI) for...

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PMID: 29525040
DOI: 10.1016/j.biopsych.2018.01.012

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