Article
Evaluation of Potential Living Kidney Donors in the APOL1 Era
9 Mar 2018
Abstract excerpt
Inheriting two apolipoprotein L1 gene (APOL1) renal risk variants accounts for the majority of the excess risk for nondiabetic ESRD in individuals with recent African ancestry.1APOL1 renal risk variants are common in blacks in the United States, with about 13% carrying two variants (defining the high-risk genotype), whereas 39% have one variant and 48% have no variant. In contrast, APOL1 renal risk variants are...
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