Article
Genetic Diversity of Cryptosporidium hominis in a Bangladeshi Community as Revealed by Whole-Genome Sequencing.
The Journal of infectious diseases - 20 Jun 2018
Gilchrist Carol A, Cotton James A, Burkey Cecelia, Arju Tuhinur, Gilmartin Allissia, Lin Ye, Ahmed Emtiaz, Steiner Kevin, Alam Masud, Ahmed Shahnawaz, Robinson Guy, Zaman Sultan Uz, Kabir Mamun, Sanders Mandy, Chalmers Rachel M, Ahmed Tahmeed, Ma Jennie Z, Haque Rashidul, Faruque Abu S G, Berriman Matthew, Petri William A
Abstract excerpt
We studied the genetic diversity of Cryptosporidium hominis infections in slum-dwelling infants from Dhaka over a 2-year period. Cryptosporidium hominis infections were common during the monsoon, and were genetically diverse as measured by gp60 genotyping and whole-genome resequencing. Recombination in the parasite was evidenced by the decay of linkage disequilibrium in the genome over <300 bp. Regions of the...
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