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Pathogenicity and virulence of Mycobacterium leprae

3 Nov 2022

Abstract excerpt

Leprosy is caused by Mycobacterium leprae (M. leprae) and M. lepromatosis, an obligate intracellular organism, and over 200,000 new cases occur every year. M. leprae parasitizes histiocytes (skin macrophages) and Schwann cells in the peripheral nerves. Although leprosy can be treated by multidrug therapy, some patients relapse or have a prolonged clinical course and/or experience leprosy reaction. These varying...

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PMID: 36326715
DOI: 10.1080/21505594.2022.2141987

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