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Article

MicroRNA as Crucial Regulators of Gene Expression in Estradiol-Treated Human Endothelial Cells

1 Jan 2018

Abstract excerpt

BACKGROUND/AIMS: Estrogen signalling plays an important role in vascular biology as it modulates vasoactive and metabolic pathways in endothelial cells. Growing evidence has also established microRNA (miRNA) as key regulators of endothelial function. Nonetheless, the role of estrogen regulation on miRNA profile in endothelial cells is poorly understood. In this study, we aimed to determine how estrogen modulates...

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PMID: 29510375
DOI: 10.1159/000487910

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