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Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder

5 Mar 2018

Abstract excerpt

Abstract The Wnt signaling pathway plays a crucial role in neurodevelopment and in regulating the function and structure of the adult nervous system. Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental disorders with evidence of subtle neurodevelopmental, structural and functional neuronal abnormalities. We aimed to elucidate the role of aberrant regulation of the Wnt system in these disorders by...

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PMID: 29507296
DOI: 10.1038/s41398-018-0102-1

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