Article
The ups and downs of Wnt signaling in prevalent neurological disorders.
Oncogene - 4 Dec 2006
De Ferrari G V, Moon R T
Abstract excerpt
In order to function properly, the brain must be wired correctly during critical periods in early development. Mistakes in this process are hypothesized to occur in disorders like autism and schizophrenia. Later in life, signaling pathways are essential in maintaining proper communication between neuronal and non-neuronal cells, and disrupting this balance may result in disorders like Alzheimer's disease. The...
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