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Article

Coagulopathy induced by traumatic brain injury: systemic manifestation of a localized injury.

Blood - 3 May 2018

Zhang Jianning, Zhang Fangyi, Dong Jing-Fei

Abstract excerpt

Traumatic brain injury (TBI)-induced coagulopathy is a common and well-recognized risk for poor clinical outcomes, but its pathogenesis remains poorly understood, and treatment options are limited and ineffective. We discuss the recent progress and knowledge gaps in understanding this lethal complication of TBI. We focus on (1) the disruption of the brain-blood barrier to disseminate brain injury systemically by...

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Identifiers

PMID: 29507078
DOI: 10.1182/blood-2017-11-784108
PMCID: PMC5934798

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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