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Article

Contribution of factor VII polymorphisms to coagulopathy in patients with isolated traumatic brain injury.

Clinical neurology and neurosurgery - 1 Sept 2021

Fang Jiang, Yuan Qiang, Du Zhuoying, Liu Chaobo, Xu Hao, Yang Weijian, Chen Long, Zhao Jianlan, Xie Rong, Hu Jin, Wu Xing

Abstract excerpt

BACKGROUND: Coagulopathy is a severe complication of traumatic brain injury (TBI) and can cause secondary injuries and death. Decrease of FVII activity contributes to the coagulopathy and progressive hemorrhagic injury (PHI) in patients with isolated TBI. Some polymorphic loci of coagulation factor VII (FVII) are shown to be essential for FVII activity. However, the relationship between FVII gene polymorphisms...

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Identifiers

PMID: 34371385
DOI: 10.1016/j.clineuro.2021.106836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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