Perioperative chemotherapy with or without epidermal growth factor receptor blockade in unselected patients with locally advanced oesophagogastric adenocarcinoma: Randomized phase II study with advanced biomarker program of the German Cancer Society (AIO/CAO STO-0801).

doi:10.1016/j.ejca.2018.01.079

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Perioperative chemotherapy with or without epidermal growth factor receptor blockade in unselected patients with locally advanced oesophagogastric adenocarcinoma: Randomized phase II study with advanced biomarker program of the German Cancer Society (AIO/CAO STO-0801).

European journal of cancer (Oxford, England : 1990) - 1 Apr 2018

Stahl Michael, Maderer Annett, Lordick Florian, Mihaljevic Andre L, Kanzler Stefan, Hoehler Thomas, Thuss-Patience Peter, Mönig Stefan, Kunzmann Volker, Schroll Sebastian, Sandermann Andreas, Tannapfel Andrea, Meyer Hans-Joachim, Schuhmacher Christoph, Wilke Hansjochen, Moehler Markus

Abstract excerpt

BACKGROUND: Perioperative chemotherapy significantly improves survival in patients with locally advanced oesophagogastric cancer (EGC). However, as approximately 60% of patients will die from their disease, new therapeutic agents such as molecular-targeted drugs are needed. PATIENTS AND METHODS: To evaluate the role of panitumumab with perioperative chemotherapy, previously untreated patients with locally...

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PMID: 29501977
DOI: 10.1016/j.ejca.2018.01.079

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EGFR
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