Article
Global phenotypic characterisation of human platelet lysate expanded MSCs by high-throughput flow cytometry.
Scientific reports - 2 Mar 2018
Reis Monica, McDonald David, Nicholson Lindsay, Godthardt Kathrin, Knobel Sebastian, Dickinson Anne M, Filby Andrew, Wang Xiao-Nong
Abstract excerpt
Mesenchymal stromal cells (MSCs) are a promising cell source to develop cell therapy for many diseases. Human platelet lysate (PLT) is increasingly used as an alternative to foetal calf serum (FCS) for clinical-scale MSC production. To date, the global surface protein expression of PLT-expended MSCs (MSC-PLT) is not known. To investigate this, paired MSC-PLT and MSC-FCS were analysed in parallel using...
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