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Molecular docking based screening of Noggin inhibitors

31 Jan 2018

Abstract excerpt

Noggin (NOG) a BMP (bone morphogenetic protein) antagonist plays a key role in preferentially driving a subset of breast cancer cells towards the bone and causing osteolytic lesions leading to severe pain and discomfort in the patients. Owing to its role in bone metastasis, NOG could be promising molecular target in bone metastasis and that identifying small molecule inhibitors could aid in the treatment. Towards...

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PMID: 29497255
DOI: 10.6026/97320630014015

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