Article
Association of the matrix metalloproteinases (MMPs) family gene polymorphisms and the risk of coronavirus disease 2019 (COVID-19); implications of contribution for development of neurological symptoms in the COVID-19 patients.
Molecular biology reports - 1 Jan 2023
Ramezani Samaneh, Ezzatifar Fatemeh, Hojjatipour Tahereh, Hemmatzadeh Maryam, Shabgah Arezoo Gowhari, Navashenaq Jamshid Gholizadeh, Aslani Saeed, Shomali Navid, Arabi Mohsen, Babaie Farhad, Jadidi-Niaragh Farhad, Hosseinzadeh Ramin, Feizisani Fahimeh, Khodayar Sara, Safari Roghaiyeh, Mohammadi Hamed
Abstract excerpt
BACKGROUND: Seemingly, the Matrix metalloproteinases (MMPs) play a role in the etiopathogenesis of coronavirus disease 2019 (COVID-19). Here in this study, we determined the association of MMP9 rs3918242, MMP3 rs3025058, and MMP2 rs243865 polymorphisms with the risk of COVID-19, especially in those with neurological syndrome (NS). METHODS: We enrolled 500 patients with COVID-19 and 500 healthy individuals. To...
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