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Epigenetic alterations induced by environmental stress associated with metabolic and neurodevelopmental disorders

1 Aug 2016

Abstract excerpt

Epigenetics is a gene regulation mechanism that does not depend on genomic DNA sequences but depends on chemical modification of genomic DNA and histone proteins around which DNA is wrapped. The failure of epigenetic mechanisms is known to cause various congenital disorders. It is also known that the failures of epigenetic mechanisms causes various acquired disorders since epigenetic modifications of the genome...

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PMID: 29492297
DOI: 10.1093/eep/dvw017

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