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Article

Toll-like receptors 2 and 4 gene polymorphisms in a southeastern Chinese population with tuberculosis.

International journal of immunogenetics - 1 Apr 2010

Xue Y, Zhao Z Q, Wang H J, Jin L, Liu C P, Wang Y, Li J C

Abstract excerpt

Polymorphisms of the toll-like receptor 2 (TLR2) gene (Arg677Trp, Arg753Gln) and the TLR4 gene (Asp299Gly, Thr399Ile) were investigated in 205 tuberculosis (TB) patients and 203 controls. Genetic variations were analysed by DNA sequencing. We revealed that these polymorphisms were rare in the southeastern Chinese population and were not associated with susceptibility to TB.

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Source

Identifiers

PMID: 20002809
DOI: 10.1111/j.1744-313X.2009.00892.x

Genes

TLR2
TLR4

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