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Article

Whole genome sequencing of pairwise human subjects reveals DNA mutations specific to developmental dysplasia of the hip.

Genomics - 1 May 2019

Zhu Lun-Qing, Su Guang-Hao, Dai Jin, Zhang Wen-Yan, Yin Chun-Hua, Zhang Fu-Yong, Zhu Zhen-Hua, Guo Zhi-Xiong, Fang Jian-Feng, Zou Cheng-da, Chen Xing-Guang, Zhang Ya, Xu Cai-Ying, Zhen Yun-Fang, Wang Xiao-Dong

Abstract excerpt

Developmental dysplasia of the hip (DDH) is a common congenital malformation characterized by mismatch in shape between the femoral head and acetabulum, and leads to hip dysplasia. To date, the pathogenesis of DDH is poorly understood and may involve multiple factors, including genetic predisposition. However, comprehensive genetic analysis has not been applied to investigate a genetic component of DDH. In the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29486210
DOI: 10.1016/j.ygeno.2018.02.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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