Article
The genetics of leprosy.
Annals of human biology - 1 Jan 2000
Serjeantson S, Wilson S R, Keats B J
Abstract excerpt
Population and family distributions of leprosy in the Bogia Subprovince of Papua New Guinea have been examined for evidence of inherited susceptibility to the disease. Evidence for multigenic inheritance of leprosy severity is provided by the restriction of pleiotropy with red-cell enzyme 6PGD phenotypes to a single clinical form of leprosy and by the superior fit of pedigree data to a multifactorial, rather than...
Topics
- Blood Group Antigens
- Epidemiologic Methods
- Gene Frequency
- Genetic Markers
- Genetics, Population
- Genotype
- Humans
- Leprosy
- Mathematics
- New Guinea
- Phenotype
- Phosphogluconate Dehydrogenase