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Article

Toxic stress history and hypothalamic-pituitary-adrenal axis function in a social stress task: Genetic and epigenetic factors.

Neurotoxicology and teratology - 1 Jan 2000

Lapp Hannah E, Ahmed Sarah, Moore Celia L, Hunter Richard G

Abstract excerpt

Histories of early life stress (ELS) or social discrimination can reach levels of severity characterized as toxic to mental and physical health. Such toxic social stress during development has been linked to altered acute hypothalamic-pituitary-adrenal (HPA) response to social stress in adulthood. However, there are important individual differences in the size and direction of these effects. We explored...

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Source

Identifiers

PMID: 29475055
DOI: 10.1016/j.ntt.2018.01.011

Genes

FKBP5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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