Article
The B allele with a 5·8 kb deletion in intron 1 of the ABO gene is the major allele in Japanese individuals with Bm and A1 Bm phenotypes.
Vox sanguinis - 1 May 2018
Ogasawara K, Miyazaki T, Ito S, Yabe R, Uchikawa M, Enomoto T, Yokoya N, Hori Y, Kumamoto M, Watanabe S, Satake M
Abstract excerpt
Bm and A1 Bm phenotypes are the most frequent ABO variants in the Japanese population. The B antigen on Bm red blood cells is only detectable by adsorption and elution tests, and plasma B-transferase activity is usually detected at half or less levels compared with that of common B. Recently, a B allele lacking an erythroid cell-specific transcription enhancer in intron 1 of the ABO gene was identified from...
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