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Structural and advanced imaging in predicting MGMT promoter methylation of primary glioblastoma: a region of interest based analysis

21 Feb 2018

Abstract excerpt

BACKGROUND: The methylation status of oxygen 6-methylguanine-DNA methyltransferase (MGMT) promoter has been associated with treatment response in glioblastoma(GBM). Using pre-operative MRI techniques to predict MGMT promoter methylation status remains inconclusive. In this study, we investigated the value of features from structural and advanced imagings in predicting the methylation of MGMT promoter in primary...

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PMID: 29467012
DOI: 10.1186/s12885-018-4114-2

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