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Article

Radiomics signature: A potential biomarker for the prediction of MGMT promoter methylation in glioblastoma

19 Sept 2017

Abstract excerpt

Background In glioblastoma (GBM), promoter methylation of the DNA repair gene O ‐methylguanine‐DNA methyltransferase (MGMT) is associated with beneficial chemotherapy. Purpose/Hypothesis To analyze radiomics features for utilizing the full potential of medical imaging as biomarkers of MGMT promoter methylation. Study Type Retrospective. Population/Subjects In all, 98 GBM patients with known MGMT (48 methylated...

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Share to Chromatin Remodeling and Cancer
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28926163
DOI: 10.1002/jmri.25860

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